How do different exercise modalities (cardiovascular vs resistance) differentially regulate exerkine-LTP pathways to optimize cognitive outcomes?

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Description

The review notes that exerkine levels vary by exercise type and duration, but the mechanistic basis for designing individualized exercise programs remains unclear. Understanding these differential pathways could enable precision exercise prescriptions for cognitive enhancement and neuroprotection.

Gap type: open_question Source paper: Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity. (2022, Frontiers in neuroendocrinology, PMID:35283168)

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