What specific mechanisms link electroacupuncture's diverse molecular effects to clinical spasticity reduction?

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Description

The study shows EA affects multiple pathways (neurotransmitters, inflammation, oxidative stress, neuroplasticity) but doesn’t explain how these diverse molecular changes mechanistically converge to reduce spasticity. Understanding this integration is critical for optimizing treatment protocols and identifying key therapeutic targets.

Gap type: unexplained_observation Source paper: The mechanism of electroacupuncture treatment for post-stroke spasticity: A systematic review and Meta-analysis. (2026, Behavioural brain research, PMID:41101592)

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