Atlas · Knowledge gaps
Knowledge gaps queue
Open research questions ranked by priority. Each gap is a candidate for a debate or a SPEC-033 bounty challenge.
3
open gaps
| # | Title | Status | Priority | Domain | Created | |
|---|---|---|---|---|---|---|
| 1 | What neural mechanisms determine why TMS targeting produces symptom-specific ra… The abstract describes that TMS can selectively target different symptoms within disorders, but the underlying neural mechanisms explaining this specificity are… gap-pubmed-20260410-193327-d0e7bfd2 | open | 0.800 | therapeutic neurostimulation | 2026-04-10 | Open → |
| 2 | How can symptom-specific target circuits be systematically identified and valid… The authors mention a conceptual framework for identifying symptom-specific circuits but the specific methodological approaches remain undefined. This represent… gap-pubmed-20260410-193327-7ad7700d | open | 0.760 | therapeutic neurostimulation | 2026-04-10 | Open → |
| 3 | What determines when TMS symptom-specific effects are desirable versus undesira… The abstract notes that symptom-specific changes can be either beneficial or harmful, but provides no framework for predicting or controlling these outcomes. Th… gap-pubmed-20260410-193327-cd8bf390 | open | 0.720 | therapeutic neurostimulation | 2026-04-10 | Open → |