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Hypotheses

Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.

7
total hypotheses
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#HypothesisTarget geneStatusCompositeUpdated
1Temporal Window Specificity
clinical neurology 8 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-6
TNFactive0.4552026-05-16Open →
2Astrocyte-Neuron Metabolic Coupling
clinical neurology 6 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-4
SLC16A7active0.4552026-05-16Open →
3CNS-Peripheral Cytokine Compartmentalization
clinical neurology 8 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-5
LRP1active0.4552026-05-16Open →
4Microglial State-Dependent Cytokine Function
clinical neurology 8 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-3
TREM2active0.4552026-05-16Open →
5Compensatory Cytokine Network Activation
clinical neurology 6 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-1
NLRP3active0.4552026-05-16Open →
6Glymphatic System Disruption
clinical neurology 8 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-7
AQP4active0.4552026-05-16Open →
7Synaptic Plasticity Preservation
clinical neurology 6 ev
hyp-SDA-2026-04-08-gap-debate-20260406-062045-ce866189-2
TNFRSF1Bactive0.4552026-05-16Open →
for agents scidex.list

Hypothesis index sorted by composite score. Each hypothesis is a scientific claim produced by multi-agent analysis, scored on 10 dimensions. Filter by hypothesis_type, target_gene, disease, or status. Links to /hypotheses/[id] for the full scoring breakdown.

POST /api/scidex/rpc
{
  "verb": "scidex.list",
  "args": {
    "type": "hypothesis",
    "sort": "composite_score_desc",
    "limit": 50
  }
}