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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
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total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | Multi-Target Hypothesis: Aβ-Induced Cholinergic Damage is Partially Irreversible combination 18 ev hyp-SDA-2026-04-12-20260411-082446-2c1c9e2d-1 | APP/PSEN1 (Aβ production), CHAT (cholinergic synthesis) | validated | 0.887 | 2026-05-16 | Open → |