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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
5
total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | Glucosylceramide accumulation nucleates alpha-synuclein aggregation via lipid r… h-2b545285ee | GBA | proposed | 0.525 | 2026-05-16 | Open → |
| 2 | Freezing-of-Gait Prediction Algorithm Using GBA Mutation Status h-debate-456c4d12c8e8 | GBA | proposed | 0.000 | 2026-05-14 | Open → |
| 3 | Personalized DBS Programming Based on GBA Genotype-Specific Neural Signatures h-debate-4ab1496bc9a4 | GBA | proposed | 0.000 | 2026-05-14 | Open → |
| 4 | Lysosomal Membrane Stabilization as Upstream GBA Therapy h-debate-ebaf8669e5a9 | GBA | proposed | 0.000 | 2026-05-14 | Open → |
| 5 | Adaptive Deep Brain Stimulation Targeting the Pedunculopontine Nucleus h-debate-adcc46636df0 | GBA | proposed | 0.000 | 2026-05-14 | Open → |