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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
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total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | HTR2A-Mediated MMP-9 Suppression Preserves BBB Integrity at Low Doses 12 ev h-SDA-2026-04-26-gap-pubmed-20260411-081101-dfe3eacb-06-htr2a-mediated-mmp-9-suppression-preserves-bbb-i-2a9039ebb3 | HTR2A, MMP-9, CLDN5 (claudin-5), TJP1 (ZO-1) | proposed | 0.425 | 2026-05-14 | Open → |