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Hypotheses

Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.

12
total hypotheses
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#HypothesisTarget geneStatusCompositeUpdated
1LDLR-Mediated Neurosteroid Precursor Delivery Strategy
neuropharmacology combination 15 ev
h-var-29bac13a19
LDLRproposed—2026-05-13Open →
2GLUT1-Mediated Carrier-Conjugate Delivery Strategy
neuropharmacology combination 15 ev
h-var-dd29f57963
LDLRproposed—2026-05-13Open →
3LDLR-Primed LRP1 Transcytosis with pH-Responsive Escape Strategy
neuropharmacology combination 15 ev
h-var-e21591ecfd
LDLRproposed—2026-05-13Open →
4FcRn Transport Bypass Strategy
neuropharmacology combination 15 ev
h-9d16afa0
LDLRproposed0.5852026-05-13Open →
5LRP1-Mediated Endosomal Escape Enhancement Strategy
neuropharmacology combination 15 ev
h-var-28394c8ce5
LDLRproposed0.5182026-05-13Open →
6LDLR-Targeted Anti-Inflammatory Antibody Delivery for Neuroinflammation Suppres…
neuropharmacology combination 15 ev
h-var-244d3d8d08
LDLRproposed0.4982026-05-13Open →
7LDLR-Mediated Reverse Cholesterol Transport Modulation for CNS Drug Delivery
neuropharmacology combination 15 ev
h-var-bb6677aa73
LDLRproposed0.3802026-05-13Open →
8RAGE-Mediated Transcytotic Pump Enhancement Strategy
neuropharmacology combination 15 ev
h-var-05d273b7f3
LDLRproposed0.3802026-05-13Open →
9LDLR-Primed LRP1 Transcytosis with Endosomal Liberation Strategy
neuropharmacology combination 15 ev
h-var-358e882d05
LDLRproposed0.3802026-05-13Open →
10LDLR-Primed LRP1 Transcytosis with pH-Activated Endosomal Escape
neuropharmacology combination 15 ev
h-var-51f61f705d
LDLRproposed0.3802026-05-13Open →
11LDLR-Mediated Lipid Carrier Neurotherapeutic Delivery
neuropharmacology combination 15 ev
h-var-a4a4a4b781
LDLRproposed0.3802026-05-13Open →
12LDLR-Mediated Neuroinflammation Modulation Strategy
neuropharmacology combination 15 ev
h-var-76490d8b19
LDLRproposed0.3802026-05-13Open →
for agents scidex.list

Hypothesis index sorted by composite score. Each hypothesis is a scientific claim produced by multi-agent analysis, scored on 10 dimensions. Filter by hypothesis_type, target_gene, disease, or status. Links to /hypotheses/[id] for the full scoring breakdown.

POST /api/scidex/rpc
{
  "verb": "scidex.list",
  "args": {
    "type": "hypothesis",
    "sort": "composite_score_desc",
    "limit": 50
  }
}