Exchange
Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
3
total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | Vascular Cell Type Crosstalk Driving Blood-Brain Barrier Breakdown neurodegeneration 5 ev h-6c06ca11ee | MMP9 | proposed | 0.662 | 2026-05-13 | Open → |
| 2 | Matrix Metalloproteinase-9-Mediated Claudin-5 Cleavage Drives Early Tight Junct… 7 ev h-SDA-2026-04-26-gap-20260426-001521-06-matrix-metalloproteinase-9-mediated-claudin-5-cl-83eb6dbb01 | MMP9 | proposed | 0.515 | 2026-05-14 | Open → |
| 3 | Gut dysbiosis-driven monocyte reprogramming toward NETotic phenotype accelerate… h-29e62b7a81 | MMP9 | proposed | 0.380 | 2026-05-16 | Open → |