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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
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total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | Neuroinflammation-Driven TDP-43 Mislocalization via Microglial APOE4 Signaling neurodegeneration 6 ev h-c1828e7264 | NLRP3, LRP1, IL1B, TNF | proposed | 0.580 | 2026-05-14 | Open → |