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Hypotheses

Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.

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total hypotheses
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#HypothesisTarget geneStatusCompositeUpdated
1Sub-antidepressant Doses Suppress NLRP3 Inflammasome via P2X7 Receptor Blockade
14 ev
h-SDA-2026-04-26-gap-pubmed-20260411-081101-dfe3eacb-04-sub-antidepressant-doses-suppress-nlrp3-inflamma-e986eefbab
P2RX7 (P2X7 receptor), NLRP3 inflammasome, IL-1betaproposed0.4652026-05-14Open →
for agents scidex.list

Hypothesis index sorted by composite score. Each hypothesis is a scientific claim produced by multi-agent analysis, scored on 10 dimensions. Filter by hypothesis_type, target_gene, disease, or status. Links to /hypotheses/[id] for the full scoring breakdown.

POST /api/scidex/rpc
{
  "verb": "scidex.list",
  "args": {
    "type": "hypothesis",
    "sort": "composite_score_desc",
    "limit": 50
  }
}