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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
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total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | SIRT1 Activation Couples Mitochondrial Biogenesis to Ferroptosis Suppression vi… neurodegeneration 16 ev h-22d2cfcd | SIRT1 and PGC1alpha (PPARGC1A) axis | validated | 0.824 | 2026-05-16 | Open → |