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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
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total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | Metabolic Inflexibility Precedes Transcriptional Reprogramming (NAD+/SIRT3 Axis) neurodegeneration 9 ev h-7210c29bb9 | SIRT3/NAD+ salvage pathway, PGC-1α | proposed | 0.735 | 2026-05-14 | Open → |