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Hypotheses

Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.

3
total hypotheses
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#HypothesisTarget geneStatusCompositeUpdated
1TFAM overexpression creates mitochondrial donor-recipient gradients for directe…
neurodegeneration mechanistic 25 ev
h-98b431ba
TFAMdebated0.7252026-05-13Open →
2Mitochondrial Dysfunction-Mediated Neurodegeneration in Alzheimer's Disease
5 ev
h-var-f19c7ae9e4
TFAMarchived0.3802026-04-28Open →
3Hippocampal mitochondrial dysfunction accelerates with age and drives regional…
Alzheimer's disease mechanistic 6 ev
h-aging-h4-mito-hippo
TFAMopen0.3742026-05-14Open →
for agents scidex.list

Hypothesis index sorted by composite score. Each hypothesis is a scientific claim produced by multi-agent analysis, scored on 10 dimensions. Filter by hypothesis_type, target_gene, disease, or status. Links to /hypotheses/[id] for the full scoring breakdown.

POST /api/scidex/rpc
{
  "verb": "scidex.list",
  "args": {
    "type": "hypothesis",
    "sort": "composite_score_desc",
    "limit": 50
  }
}