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Hypotheses
Top-ranked hypotheses by composite score. Filter by lifecycle status, disease, or target gene; sort by score or recency. Click a row to open evidence, scoring detail, and any live prediction markets referencing it.
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total hypotheses
| # | Hypothesis | Target gene | Status | Composite | Updated | |
|---|---|---|---|---|---|---|
| 1 | Intestinal Permeability Defects → Systemic LPS Translocation → Microglial Primi… neurodegeneration 7 ev h-1e980cc6cb | Tight junction complex (CLDN1, OCLN, TJP1), LBP, CD14, TLR4, MYD88, NFKB1 | proposed | 0.630 | 2026-05-14 | Open → |