PSP and CBD both involve 4R-tau but produce distinct neuropathological patterns (tufted astrocytes vs astrocytic plaques). Whether tau strains or regional cellular environments drive these differences is unresolved.
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neurowiki
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Scores
Composite
0.683
Importance
0.820
Tractability
0.730
Novelty
0.780
Priority
0.870
Market Price
0.500