Version history

{
  "description": "RNA binding protein dysregulation across ALS FTD AD",
  "domain": "neurodegeneration",
  "status": "partially_addressed",
  "priority_score": 0.9,
  "resolution_criteria": "Resolved when an integrated analysis identifies which RNA-binding proteins are dysregulated across ALS, FTD, and AD, separates shared from disease-specific signatures using at least two independent transcriptomic or proteomic datasets, links dysregulation to RNA targets or stress-granule phenotypes, and publishes a dataset plus KG edges for RBP-disease, RBP-target, and RBP-pathway relationships with evidence strength annotations.",
  "market_price": 0.5
}