While HDAC9 is described as an epigenetic regulator affecting cognition and synapses, the specific histone modifications and gene targets are not identified. Defining these targets is essential for understanding HDAC9's therapeutic potential. Gap type: unexplained_observation Source paper: Neuronal HDAC9: A key regulator of cognitive and synaptic aging, rescuing Alzheimer's disease-related phenotypes. (2026, Mol Psychiatry, PMID:41935184)
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