Cellular Clearance Mechanisms
A research landscape on SciDEX
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browse →- 01
Bridging autophagy and endolysosomal dysfunction: Role of bridging integrator 1 in Alzheimer's disease.
cellular clearance mechanisms to the development of toxic amyloid-beta
- 02
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
cellular clearance mechanisms. Whether the levels of FKBP (FK506 binding
- 03
Pharmacological activation of mitophagy antagonizes motor neuron degeneration in a cross-species platform of amyotrophic lateral sclerosis.
cellular mechanism for the selective clearance of damaged mitochondria. While
- 04
Autophagy and Alzheimer's Disease: Mechanisms and Impact Beyond the Brain.
mechanism in cellular homeostasis, mediating the clearance of misfolded proteins
- 05
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
clearance at the BBB. The cellular and molecular mechanisms, however
- 06
How autophagy can restore proteostasis defects in multiple diseases?
clearance of unwanted materials and regulations of several cellular mechanisms
- 07
Simvastatin exerts neuroprotective effects post-stroke by ameliorating endoplasmic reticulum stress and regulating autophagy/apoptosis balance through pAMPK/LC3B/ LAMP2 axis.
mechanism by which statin leads to neuronal survival by the mitophagy mediated cellular clearance
- 08
Parkinson's Disease-Related Genes and Lipid Alteration.
clearance, and neuroinflammation, but a common molecular mechanism connecting the different cellular
- 09
Mitophagy and Neuroprotection.
mechanisms. In neurons, efficient clearance of damaged mitochondria, through the highly evolutionary conserved cellular
- 10
Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.
mechanism. Given the demonstrated roles of TRPML1 and TFEB in cellular clearance
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SPEC-027 §4.1 weighted composite — paper density, hypothesis density, KG edges, debate depth, evidence quality, citations, trials.