Oxidative Stress Biology
A research landscape on SciDEX
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Mitochondrial dysfunction and oxidative stress in Parkinson's disease: mechanisms, biomarkers, and therapeutic strategies.
oxidative stress. It also examines genetic and environmental contributors, emerging biomarkers, and future treatment strategies. METHODS: An extensive literature review was conducted, focusing on mitochondrial biology
- 02
Towards a modern definition of vitamin E-evidence for a quinone hypothesis.
biological and pharmacological activity of the tocoquinone natural product, α-tocopherol quinone (ATQ); an oxidative metabolite of α-tocopherol. ATQ is a potent cellular protectant against oxidative stress
- 03
Changes in mitochondrial glutathione levels and protein thiol oxidation in ∆yfh1 yeast cells and the lymphoblasts of patients with Friedreich's ataxia.
oxidative stress. Frataxin deficiency is also associated with severe impairment of glutathione homeostasis and changes in glutathione-dependent antioxidant defenses. The potential biological
- 04
Oxidative stress in cancer: from tumor and microenvironment remodeling to therapeutic frontiers.
oxidative stress in cancer biology and its therapeutic implications. By integrating
- 05
Oxidative stress and inflammation mediate the adverse effects of cadmium exposure on all-cause and cause-specific mortality in patients with diabetes and prediabetes.
oxidative stress and inflammation biomarkers, while Cox regression and RCS evaluated their effects on mortality. Causal mediation analysis identified biological
- 06
Discovery of Taxus chinensis fruit wine as potentially functional food against Alzheimer's disease by UHPLC-QE-MS/MS, network pharmacology and molecular docking.
biological events, including oxidative stress, inflammatory response, neuronal apoptosis, insulin
- 07
Ethanol Induced Oxidative Stress in the Vasculature: Friend or Foe.
oxidative stress in vascular biology and how ethanol consumption may alter
- 08
SIRT3: A potential therapeutic target for liver fibrosis.
biological processes, including oxidative stress, inflammation, DNA damage, and apoptosis
- 09
A multi-omics approach identifies the key role of disorders of sphingolipid metabolism in Ang II-induced hypertensive cardiomyopathy myocardial remodeling.
biological processes, including oxidative stress and excessive mitochondrial autophagy, mediated
- 10
Genome-Wide Screen of the Hippocampus in Aged Rats Identifies Mitochondria, Metabolism and Aging Processes Implicated in Sevoflurane Anesthesia.
biological process, 16 of molecular function and 18 of the cellular components were identified by Gene Ontology (GO) and KEGG analysis. Among them, oxidative stress
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SPEC-027 §4.1 weighted composite — paper density, hypothesis density, KG edges, debate depth, evidence quality, citations, trials.