What resolves this contention: Cortical implementation of delay-period short-te…

What resolves this contention: Cortical implementation of delay-period short-term memory differs across mouse association areas: PPC implements a sequence-based dynamic code whose individual cells are transiently active (paper A), whereas ALM maintains stable, perturbation-robust selective persistent activity recoverable across hemispheres (paper B). Whether sequence vs. fixed-point coding is region-specific, task-specific, or technique-specific (two-photon GCaMP vs. extracellular spikes) is unresolved. / During working memory decision tasks, the PPC may therefore perform computations through sequence-based circuit dynamics, rather than long-lived stable states, implemented using anatomically intermingled microcircuits. / We show that preparatory activity is remarkably robust to large-scale unilateral silencing: detailed neural dynamics that drive specific future movements were quickly and selectively restored by the