What resolves this contention: Both studies argue that mouse ALM preparatory activity is not maintained by local recurrence alone but by a multi-region loop; they nonetheless implicate different external partners (thalamus vs. cerebellar nuclei). The relative contributions of thalamic versus cerebellar input to maintaining cortical persistent activity — and whether they act in parallel, serially, or as redundant supports — remain to be quantitatively dissected. / Photoinhibition of the thalamus caused a short-latency and near-complete collapse of ALM activity. / The silencing of frontal cortex activity abolished preparatory activity in the cerebellar nuclei, and fastigial activity was necessary to maintain cortical preparatory activity.
Replication
No replications yet
Discussion
No comments yet — be the first.