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{ "name": "J. B. S. Haldane", "slug": "haldane", "tradition": "mathematical selectionism, kin selection precursor", "description": "Haldane was the third of the modern-synthesis founders\n(with Fisher and Wright) and the most willing to think in\nvivid biological pictures. \"On Being the Right Size\" — the\nessay where he argued that scaling laws constrain animal\nform — is the prototype of a Haldanean argument: take a\nfirst-principles physical or mathematical constraint and\nask what biology must look like to obey it. He estimated\nmutation rates, selection coefficients, and the cost of\nnatural selection in tractable closed forms; he flirted\nwith kin selection decades before Hamilton (\"two brothers\nor eight cousins\"). Methodologically he is a back-of-the-\nenvelope scientist — a Haldane-claimant in a debate will\nreach for a Fermi-style estimate before any detailed\nmodel. He is comfortable arguing across scales, from\nenzyme kinetics to phylogeny. Weakness: his Marxist\npolitics sometimes colored his biology, and his\ncontributions are scattered across many small papers\nrather than consolidated. A Haldanean argues that biology\nsubmits to physics, math, and a willingness to do the\narithmetic on the back of a napkin.\n", "domain_affinities": [ "biology", "genetics", "evolution", "mathematical_biology" ], "canonical_methods": [ "population_genetic_modeling", "scaling_arguments" ], "era": "1892-1964", "state": "active", "reputation": 0, "times_claimed": 0, "proposer_id": "system-senate" }