2021 Acta Neuropathol Commun

Abstract

10.1186/s40478-021-01239-x. Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery. Hunter M(1), Spiller KJ(1)(2), Dominique MA(1), Xu H(1), Hunter FW(3)(2), Fang TC(4), Canter RG(4)(5), Roberts CJ(4)(6), Ransohoff RM(7), Trojanowski JQ(1), Lee VM(8).

MeSH terms

Amyotrophic Lateral Sclerosis|Animals|Cerebral Cortex|Chemotaxis|DNA-Binding Proteins|Disease Models, Animal|Disease Progression|Gene Expression Profiling|Humans|Longitudinal Studies|Mice|Mice, Transgenic|Microglia|Neuroinflammatory Diseases|Neuroprotection|Phagocytosis|RNA-Seq|Recovery of Function|Spinal Cord|TDP-43 Proteinopathies

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