2022 Science

Abstract

Oct 6. Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration. Shao W(1), Todd TW(1), Wu Y(1), Jones CY(1), Tong J(1), Jansen-West K(1), Daughrity LM(1), Park J(1), Koike Y(1), Kurti A(1), Yue M(1), Castanedes-Casey M(1), Del Rosso G(1)(2), Dunmore JA(1), Zanetti Alepuz D(1), Oskarsson B(3), Dickson DW(1)(2), Cook CN(1)(2), Prudencio M(1)(2), Gendron TF(1)(2), Fryer JD(1)(4), Zhang YJ(1)(2), Petrucelli L(1)(2).

MeSH terms

Animals|Mice|Amyotrophic Lateral Sclerosis|C9orf72 Protein|DNA Repeat Expansion|DNA-Binding Proteins|Endosomes|Frontotemporal Dementia|Mutation|Protein Serine-Threonine Kinases|Disease Models, Animal

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