SIRT1 and SIRT6: The role in aging-related diseases.

Biochim Biophys Acta Mol Basis Dis 2023

You Y, Liang W

Abstract

Aging is characterized by progressive functional deterioration with increased risk of mortality. It is a complex biological process driven by a multitude of intertwined mechanisms such as increased DNA damage, chronic inflammation, and metabolic dysfunction. Sirtuins (SIRTs) are a family of NAD

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