Chemokine-defined macrophage niches establish spatial organization of tumor immunity.

Nat Immunol 2026

Ghosh S, Li X, Rawat K, Dighal A, Kalinowski S et al.

Abstract

Macrophages are among the most abundant immune cells in solid tumors, yet how macrophage lineage and spatial organization shape antitumor immunity remains unclear. Here we uncovered a division of labor between tissue-resident CD206

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