Discovery of Potent Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) Inhibitors with Antiferroptotic Properties.

J Med Chem 2025

Charnelle E, Gobert A, Marteau R

Abstract

Epub 2025 Jul 19. Discovery of Potent Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) Inhibitors with Antiferroptotic Properties. Charnelle E(1), Gobert A(1), Marteau R(2), Pautric M(1)(3), Renault N(4), Jonneaux A(1)(3), Mazhari Dorooee D(2), Laversin A(1), Devedjian JC(1)(3), Melnyk P(1), Yous S(1), Devos D(1)(3), Frédérick R(2), Ravez S(1), El Bakali J(1).

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