Mechanisms of vascular disease in dementia: what does industry want to know?

Clinical science (London, England : 1979) 2017

["Wren Paul B", "Hill Derek", "Lockhart Andrew"]

Abstract

Despite recent advances in basic and clinical science, dementia remains an area of high unmet medical need. The role of cerebrovascular mechanisms in the pathogenesis and progression of cognitive and functional impairment in dementia is being revived. In order to facilitate the development of therapeutic approaches, it is critical that a number of fundamental elements are integrated into research strategies investigating cerebrovascular pathologies as these will maximize the opportunity of bringing medicines to patients in a timely manner.

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