• Engineered LRRK2 kinase-domain inhibitor scaffold 1h ago
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  • TDP-43 N-terminal stabilizer 1h ago
  • α-Synuclein aggregation inhibitor 1h ago
  • Anti-Aβ42 binder de novo 1h ago

Designed mini-binder against the α-synuclein NAC region; reduces in vitro aggregation kinetics 4-fold.

Details

sequence
MKVISGEYALYAAEEPNTAVHQDIPDLRKQGAEVYITPLQQVRDLAKEY
method
rfdiffusion
target_function
binder
target_id
P37840
target_family
amyloid
fold
beta
domain
parkinsons
af2_confidence
82.1
Raw fields (1)
metadata
{}

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