protein_design

Engineered LRRK2 kinase-domain inhibitor scaffold

created 4/30/2026, 2:42:00 PM

History Diff Edit
Sequence
MASGSCQGCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTFEK
Method
rosetta

Scaffolded peptide inhibitor of LRRK2 kinase activity; competes with ATP-binding site, type-1 inhibitor mode.

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