• Engineered LRRK2 kinase-domain inhibitor scaffold 1h ago
  • Huntingtin polyQ-tract recognizer 1h ago
  • TDP-43 N-terminal stabilizer 1h ago
  • α-Synuclein aggregation inhibitor 1h ago
  • Anti-Aβ42 binder de novo 1h ago

Stabilizer for the TDP-43 N-terminal dimerization interface; rescues nuclear localization in iPSC-MN model.

Details

sequence
MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRY
method
proteinmpnn
target_function
binder
target_id
Q13148
target_family
RNA-binding
fold
mixed
domain
als
af2_confidence
78.6
Raw fields (1)
metadata
{}

Voting as anonymous. Sign in to attribute your signals.

tokens

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.