Version history

1 version on record. Newest first; the live version sits at the top with a live indicator.

Live

4/4/2026, 5:13:17 AM

Content snapshot

{
  "sequence": "MEPLRPGWLLLVSLAQVALGGPPPGPRPGLWAWEGRVREGPRLPAAGTAVPPPGAVWQLEDGRTMCFARHGPLSLGADVAAVSWLRGAVGRGLAAAVLLAVALLVLWLTRRAGRSRKDTIEVPVEEPPHVFVVFTDADTHPKELLLFCTQSDLCFQAQQSVHQWAEFNGSSVVPDCCHPLHPGSSLVGALLREPQEVLLHRLPDAIQGLSLVIKDVQEGDMFHCVWQDWGMPSPQMPQQVEPAYHPKVFAGQVMVTQCVQHDCFALRQPSGREPDHPG",
  "target_protein": "Aβ oligomers",
  "score": 0.75,
  "method": "alphafold",
  "metadata": {
    "method": "alphafold",
    "sequence": "MEPLRPGWLLLVSLAQVALGGPPPGPRPGLWAWEGRVREGPRLPAAGTAVPPPGAVWQLEDGRTMCFARHGPLSLGADVAAVSWLRGAVGRGLAAAVLLAVALLVLWLTRRAGRSRKDTIEVPVEEPPHVFVVFTDADTHPKELLLFCTQSDLCFQAQQSVHQWAEFNGSSVVPDCCHPLHPGSSLVGALLREPQEVLLHRLPDAIQGLSLVIKDVQEGDMFHCVWQDWGMPSPQMPQQVEPAYHPKVFAGQVMVTQCVQHDCFALRQPSGREPDHPG",
    "mutations": [],
    "uniprot_id": "Q9NZC2",
    "plddt_score": 0.89,
    "binding_affinity": {
      "kd_nm": 850,
      "target": "Aβ oligomers"
    },
    "design_rationale": "Wild-type ectodomain structure as baseline for optimization",
    "predicted_stability": 0.72
  }
}