Validation depth
Evidence breadth across identification strategies, from computational inference to randomised clinical evidence.
Computational eQTL, LLM-inferred 1 edge
Pre-clinical Knockout (KO)
Observational Cohort, case-control
Clinical RCT, Mendelian randomisation
LLM-inferred 1
Causal edges (1)
Upstream drivers pointing at synaptic vesicle release failure as the downstream effect.
- molecular_event:UNC13A cryptic exon inclusion → synaptic vesicle release failure LLM-inferred low