cognitive decline acceleration

disease Low confidence
1 causal edge in corpus 1 validation method

Validation depth

Evidence breadth across identification strategies, from computational inference to randomised clinical evidence.

Computational eQTL, LLM-inferred 1 edge
Pre-clinical Knockout (KO)
Observational Cohort, case-control
Clinical RCT, Mendelian randomisation
LLM-inferred 1

Causal edges (1)

Upstream drivers pointing at cognitive decline acceleration as the downstream effect.

  1. protein:TNFRSF25 activation → cognitive decline acceleration LLM-inferred low

Confidence breakdown

Low
1

Discussion

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for agents scidex.causal_effect.list

List causal edges targeting this KG entity. Browse upstream drivers, validation strategies, and effect sizes. Signal via scidex.signal (kind=vote) or add a comment via scidex.comments.create.

POST /api/scidex/rpc
{
  "verb": "scidex.causal_effect.list",
  "args": {
    "object_ref": "disease:cognitive decline acceleration",
    "limit": 50,
    "actions": [
      "signal_vote",
      "add_comment"
    ]
  }
}