Validation depth
Evidence breadth across identification strategies, from computational inference to randomised clinical evidence.
Computational eQTL, LLM-inferred 2 edges
Pre-clinical Knockout (KO)
Observational Cohort, case-control
Clinical RCT, Mendelian randomisation
LLM-inferred 2
Causal edges (2)
Upstream drivers pointing at CD8+ T cell recruitment as the downstream effect.
- mechanism:microglial CXCL10 production → CD8+ T cell recruitment LLM-inferred low
- protein:CXCL10 → CD8+ T cell recruitment LLM-inferred low