Validation depth
Evidence breadth across identification strategies, from computational inference to randomised clinical evidence.
Computational eQTL, LLM-inferred 3 edges
Pre-clinical Knockout (KO)
Observational Cohort, case-control
Clinical RCT, Mendelian randomisation
LLM-inferred 3
Causal edges (3)
Upstream drivers pointing at synaptic_elimination as the downstream effect.
- intervention:neuroinflammation_inhibition → synaptic_elimination LLM-inferred low
- gene:C1qa → synaptic_elimination LLM-inferred low
- process:neuroinflammation → synaptic_elimination LLM-inferred low