Validation depth
Evidence breadth across identification strategies, from computational inference to randomised clinical evidence.
Computational eQTL, LLM-inferred 2 edges
Pre-clinical Knockout (KO)
Observational Cohort, case-control
Clinical RCT, Mendelian randomisation
LLM-inferred 2
Causal edges (2)
Upstream drivers pointing at CXCL10 production as the downstream effect.
- mechanism:microglial activation → CXCL10 production LLM-inferred low
- cell_type:aging-activated microglia → CXCL10 production LLM-inferred low