Version history

1 version on record. Newest first; the live version sits at the top with a live indicator.

  1. Live 68ccd0a5d203
    5/17/2026, 4:35:28 PM
    Content snapshot
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      "prompt": "Vulnerability, Development, and Individual Differences: Why Not Everyone Becomes Addicted figure 1",
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      "raw_fields": {
        "name": "Adverse childhood experiences and addiction risk: dose-response relationship",
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          {
            "doi": "10.1523/jneurosci.0406-21.2021",
            "value": "p>2",
            "cite_key": "Christian2021",
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            "value_source_sentence": "In rats, the expression of incubation ultimately depends on Ca<sup>2+</sup>-permeable AMPARs that accumulate in synapses onto medium spiny neurons (MSNs) in the NAc core."
          },
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            "doi": "10.3390/ijms251910529",
            "value": "20%",
            "cite_key": "ElMostafi2024",
            "n_analyzed": null,
            "n_definition": "participants in epidemiological study",
            "scope_region": "general population / clinical",
            "scope_population": "adults with ACE history",
            "value_source_sentence": "Next, a two-bottle free access paradigm was performed over 10 weeks to assess intermittent 20% ethanol voluntary consumption."
          },
          {
            "doi": "10.3389/fpsyg.2025.1735137",
            "value": "26%",
            "cite_key": "Wei2026",
            "n_analyzed": 692,
            "n_definition": "participants in epidemiological study",
            "scope_region": "general population / clinical",
            "scope_population": "adults with ACE history",
            "value_source_sentence": "(2) Social anxiety (indirect effect = 0.042) and depression (indirect effect = 0.019) formed a chain mediation pathway, explaining 26% of the total effect."
          },
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            "doi": "10.3389/fpsyt.2026.1635802",
            "value": "5.8%",
            "cite_key": "Ogilvie2026",
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            "n_definition": "participants in epidemiological study",
            "scope_region": "general population / clinical",
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            "value_source_sentence": "We examined variation across trajectory groups by sex, Indigenous status (non-Indigenous/Indigenous Australians), psychiatric diagnoses associated with hospital admissions, place of residence (metropolitan, regional, remote), and socioeconomic status.<h4>Results</h4>Four distinct trajectories of MHS contacts were identified, including escalating (5.8%), low (64.5%), adolescent limited (14.5%), and childhood peak declining (15.3%) trajectories."
          },
          {
            "doi": "10.1007/s42844-026-00205-7",
            "value": "14.9%",
            "cite_key": "LaCharite2026",
            "n_analyzed": 200,
            "n_definition": "participants in epidemiological study",
            "scope_region": "general population / clinical",
            "scope_population": "adults with ACE history",
            "value_source_sentence": "Of 7,200 participants, 14.9% were arrested by age 26."
          }
        ],
        "n_definition": "study participants",
        "scope_region": "clinical/epidemiological",
        "comparison_type": "dose_response",
        "taxonomic_level": "N/A",
        "scope_population": "adults with retrospective ACE assessment",
        "homogeneity_check": "Studies vary in ACE measurement instruments, addiction outcome definitions, and population demographics. Direct quantitative comparison requires caution."
      },
      "section_id": "section_10_evidence",
      "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_10_evidence.json",
      "target_ref": "wiki_page:computationalreviewaddiction-10",
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        "paper:paper-a530a5c1d49d",
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      ],
      "section_title": "Vulnerability, Development, and Individual Differences: Why Not Everyone Becomes Addicted",
      "source_policy": {
        "mode": "public_source_pointer_with_short_context",
        "notes": [
          "Local review repositories are read-only inputs.",
          "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
        ],
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      "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_10_evidence.json",
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