Details
- kind
- infographic
- prompt
- D1 vs D2 MSN activity during cocaine self-administration phases
- provider
- other
- section_id
- section_07_evidence
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_07_evidence.json
- target_ref
- wiki_page:computationalreviewaddiction-07
- review_repo
- ComputationalReviewAddiction
- section_ref
- wiki_page:computationalreviewaddiction-07
- source_path
- evidence/section_07_evidence.json
- section_title
- Recording Realities: What In Vivo Technologies Reveal and Conceal
- generation_status
- complete
- review_bundle_ref
- analysis_bundle:ab-d95cfb705572
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_07_evidence.json
- commit_sha
- 43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction
Raw fields (3)
- raw_fields
{ "papers": [ { "doi": "10.1523/jneurosci.0108-23.2023", "value": "significant change", "method": "calcium imaging", "cite_key": "Kokane2023", "value_source_sentence": "Heroin abstinence significantly increased intrinsic excitability in D1<sup>+</sup> and D2<sup>+</sup> PL->NAc neurons and increased postsynaptic strength selectively in D1<sup>+</sup> neurons." } ], "x_axis": "Drug-taking phase", "y_axis": "Calcium signal (ΔF/F or z-score)", "n_analyzed": "varies by study", "n_definition": "animals with validated cell-type targeting", "scope_region": "nucleus accumbens", "comparison_name": "D1 vs D2 MSN activity during cocaine self-administration phases", "comparison_type": "cell-type comparison", "taxonomic_level": "cell type (Cre-defined)", "scope_population": "D1-MSNs and D2-MSNs", "homogeneity_check": "Studies use different Cre lines (D1-Cre vs Drd1-Cre), different calcium indicators (GCaMP6 vs GCaMP7), and different self-administration schedules. Direct comparison of magnitudes requires careful normalization." }- source_refs
[ "paper:paper-2a36d047f211" ]
- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction" }