Replication Status of Key Computational Model Predictions

{
  "type": "heatmap",
  "title": "Replication Status of Key Computational Model Predictions",
  "papers": [
    {
      "doi": "10.1523/jneurosci.4322-15.2016",
      "unit": "independent replications",
      "label": "Reduced model-based control in addiction: replicated",
      "value": 3,
      "cite_key": "Reiter2016",
      "value_source_sentence": "alcohol-dependent patients exhibited significantly reduced model-based control"
    },
    {
      "doi": "10.1098/rstb.2008.0094",
      "unit": "independent replications",
      "label": "CRF increase during withdrawal: replicated",
      "value": 5,
      "cite_key": "Koob2008a",
      "value_source_sentence": "Acute withdrawal from all major drugs of abuse produces increases in reward thresholds, anxiety-like responses and extracellular levels of CRF in the central nucleus of the amygdala."
    },
    {
      "doi": "10.1101/029256",
      "unit": "studies",
      "label": "Homeostatic RL escalation prediction: single study",
      "value": 1,
      "cite_key": "Keramati2015",
      "value_source_sentence": "The theory also generates unique predictions about the mechanisms of cocaine-intake regulation."
    }
  ],
  "figure_id": "fig_sec9_replication_landscape",
  "n_analyzed": 3,
  "description": "For each major model class, shows which core predictions have been independently replicated, remain single-study, or are contested",
  "n_definition": "number of independent studies supporting the prediction",
  "scope_region": "addiction neuroscience",
  "source_cluster": 8,
  "taxonomic_level": "prediction level",
  "scope_population": "core model predictions",
  "homogeneity_check": "Replication counts are approximate based on our evidence search. 'Independent replications' means studies from different labs confirming the same prediction. Single-study predictions may have unpublished replications not captured here."
}

[
  "paper:paper-36cd39d12abb",
  "paper:paper-56e452619fe3",
  "paper:paper-a99c78acffb3"
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction"
}