Version history

{
  "kind": "infographic",
  "prompt": "Replication Status of Key Computational Model Predictions",
  "provider": "other",
  "raw_fields": {
    "type": "heatmap",
    "title": "Replication Status of Key Computational Model Predictions",
    "papers": [
      {
        "doi": "10.1523/jneurosci.4322-15.2016",
        "unit": "independent replications",
        "label": "Reduced model-based control in addiction: replicated",
        "value": 3,
        "cite_key": "Reiter2016",
        "value_source_sentence": "alcohol-dependent patients exhibited significantly reduced model-based control"
      },
      {
        "doi": "10.1098/rstb.2008.0094",
        "unit": "independent replications",
        "label": "CRF increase during withdrawal: replicated",
        "value": 5,
        "cite_key": "Koob2008a",
        "value_source_sentence": "Acute withdrawal from all major drugs of abuse produces increases in reward thresholds, anxiety-like responses and extracellular levels of CRF in the central nucleus of the amygdala."
      },
      {
        "doi": "10.1101/029256",
        "unit": "studies",
        "label": "Homeostatic RL escalation prediction: single study",
        "value": 1,
        "cite_key": "Keramati2015",
        "value_source_sentence": "The theory also generates unique predictions about the mechanisms of cocaine-intake regulation."
      }
    ],
    "figure_id": "fig_sec9_replication_landscape",
    "n_analyzed": 3,
    "description": "For each major model class, shows which core predictions have been independently replicated, remain single-study, or are contested",
    "n_definition": "number of independent studies supporting the prediction",
    "scope_region": "addiction neuroscience",
    "source_cluster": 8,
    "taxonomic_level": "prediction level",
    "scope_population": "core model predictions",
    "homogeneity_check": "Replication counts are approximate based on our evidence search. 'Independent replications' means studies from different labs confirming the same prediction. Single-study predictions may have unpublished replications not captured here."
  },
  "section_id": "section_12_evidence",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_12_evidence.json",
  "target_ref": "wiki_page:computationalreviewaddiction-12",
  "review_repo": "ComputationalReviewAddiction",
  "section_ref": "wiki_page:computationalreviewaddiction-12",
  "source_path": "evidence/section_12_evidence.json",
  "source_refs": [
    "paper:paper-36cd39d12abb",
    "paper:paper-56e452619fe3",
    "paper:paper-a99c78acffb3"
  ],
  "section_title": "Synthesis: An Evidence Scorecard for Addiction Neuroscience",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction"
  },
  "generation_status": "complete",
  "review_bundle_ref": "analysis_bundle:ab-d95cfb705572",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_12_evidence.json",
  "commit_sha": "43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction"
}