Martinotti Cell Axonal Projections Across Cortical Layers in Rat Somatosensory…

{
  "papers": [
    {
      "doi": "10.1113/jphysiol.2004.073353",
      "value": "Layer I (primary), Layer II/III (secondary)",
      "method": "biocytin filling + EM",
      "metric": "primary axonal target layer for L2/3 MCs",
      "cite_key": "Wang2004",
      "condition": "somatosensory cortex, P13-16, L2/3 MCs",
      "study_system": "rat",
      "value_source_sentence": "layer II/III MCs targeted mostly layer I and to a lesser degree layer II/III"
    },
    {
      "doi": "10.1113/jphysiol.2004.073353",
      "value": "Layer IV (primary), Layer I (secondary)",
      "method": "biocytin filling + EM",
      "metric": "primary axonal target layer for L4 MCs",
      "cite_key": "Wang2004",
      "condition": "somatosensory cortex, P13-16, L4 MCs",
      "study_system": "rat",
      "value_source_sentence": "layer IV MCs targeted mostly layer IV and to a lesser degree layer I"
    },
    {
      "doi": "10.1113/jphysiol.2004.073353",
      "value": "Layer IV and Layer I (primary), home layer (secondary)",
      "method": "biocytin filling + EM",
      "metric": "primary axonal target layer for L5/6 MCs",
      "cite_key": "Wang2004",
      "condition": "somatosensory cortex, P13-16, L5/6 MCs",
      "study_system": "rat",
      "value_source_sentence": "layer V and VI MCs targeted mostly layer IV and layer I and to a lesser degree the layer in which their somata was located."
    }
  ],
  "n_analyzed": "180 total MCs across L2-L6",
  "n_definition": "individual biocytin-filled neurons from 180 total MCs",
  "scope_region": "rat somatosensory cortex",
  "comparison_id": "mc-axon-layer-targeting-rat",
  "comparison_name": "Martinotti Cell Axonal Projections Across Cortical Layers in Rat Somatosensory Cortex",
  "comparison_type": "convergent evidence",
  "taxonomic_level": "morphological subtype by laminar position",
  "what_it_reveals": "Within a single comprehensive study, Martinotti cells in different layers show distinct axonal targeting patterns, suggesting layer-specific subpopulations.",
  "scope_population": "morphologically-defined Martinotti cells (biocytin-filled, SOM+/PV-/VIP-)",
  "homogeneity_check": {
    "caveats": [
      "All data from a single study (Wang et al. 2004), so cross-lab replication not yet assessed for layer-specific breakdown",
      "Juvenile rats (P13-16) — axonal arbors may not be fully mature"
    ],
    "metric_consistent": true,
    "scope_region_uniform": true,
    "taxonomic_level_uniform": true,
    "scope_population_uniform": true
  },
  "suggested_plot_type": "grouped bar"
}

[
  "paper:paper-0cee20f3440c"
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "89b7e9787cd90e942b0adb531d549af3ddad30f1",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewSST"
}