Version history

{
  "kind": "infographic",
  "prompt": "Within a single comprehensive study, Martinotti cells in different layers show distinct axonal targeting patterns, suggesting layer-specific subpopulations.",
  "provider": "other",
  "raw_fields": {
    "papers": [
      {
        "doi": "10.1113/jphysiol.2004.073353",
        "value": "Layer I (primary), Layer II/III (secondary)",
        "method": "biocytin filling + EM",
        "metric": "primary axonal target layer for L2/3 MCs",
        "cite_key": "Wang2004",
        "condition": "somatosensory cortex, P13-16, L2/3 MCs",
        "study_system": "rat",
        "value_source_sentence": "layer II/III MCs targeted mostly layer I and to a lesser degree layer II/III"
      },
      {
        "doi": "10.1113/jphysiol.2004.073353",
        "value": "Layer IV (primary), Layer I (secondary)",
        "method": "biocytin filling + EM",
        "metric": "primary axonal target layer for L4 MCs",
        "cite_key": "Wang2004",
        "condition": "somatosensory cortex, P13-16, L4 MCs",
        "study_system": "rat",
        "value_source_sentence": "layer IV MCs targeted mostly layer IV and to a lesser degree layer I"
      },
      {
        "doi": "10.1113/jphysiol.2004.073353",
        "value": "Layer IV and Layer I (primary), home layer (secondary)",
        "method": "biocytin filling + EM",
        "metric": "primary axonal target layer for L5/6 MCs",
        "cite_key": "Wang2004",
        "condition": "somatosensory cortex, P13-16, L5/6 MCs",
        "study_system": "rat",
        "value_source_sentence": "layer V and VI MCs targeted mostly layer IV and layer I and to a lesser degree the layer in which their somata was located."
      }
    ],
    "n_analyzed": "180 total MCs across L2-L6",
    "n_definition": "individual biocytin-filled neurons from 180 total MCs",
    "scope_region": "rat somatosensory cortex",
    "comparison_id": "mc-axon-layer-targeting-rat",
    "comparison_name": "Martinotti Cell Axonal Projections Across Cortical Layers in Rat Somatosensory Cortex",
    "comparison_type": "convergent evidence",
    "taxonomic_level": "morphological subtype by laminar position",
    "what_it_reveals": "Within a single comprehensive study, Martinotti cells in different layers show distinct axonal targeting patterns, suggesting layer-specific subpopulations.",
    "scope_population": "morphologically-defined Martinotti cells (biocytin-filled, SOM+/PV-/VIP-)",
    "homogeneity_check": {
      "caveats": [
        "All data from a single study (Wang et al. 2004), so cross-lab replication not yet assessed for layer-specific breakdown",
        "Juvenile rats (P13-16) — axonal arbors may not be fully mature"
      ],
      "metric_consistent": true,
      "scope_region_uniform": true,
      "taxonomic_level_uniform": true,
      "scope_population_uniform": true
    },
    "suggested_plot_type": "grouped bar"
  },
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  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewSST/blob/89b7e9787cd90e942b0adb531d549af3ddad30f1/evidence/section_04_evidence_package.json",
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  "section_ref": "wiki_page:computationalreviewsst-04",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-0cee20f3440c"
  ],
  "section_title": "Morphological Diversity",
  "source_policy": {
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      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
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  "review_bundle_ref": "analysis_bundle:ab-8466d095488a",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewSST/blob/89b7e9787cd90e942b0adb531d549af3ddad30f1/evidence/section_04_evidence_package.json",
  "commit_sha": "89b7e9787cd90e942b0adb531d549af3ddad30f1",
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}