Version history

{
  "kind": "infographic",
  "prompt": "Loss of Rhythmically Bursting Neurons After Cholinergic Lesion",
  "provider": "other",
  "raw_fields": {
    "title": "Loss of Rhythmically Bursting Neurons After Cholinergic Lesion",
    "papers": [
      {
        "n": null,
        "doi": "10.1152/jn.1998.79.4.1633",
        "value": "41% control vs 17% lesioned",
        "method": "extracellular single unit recording",
        "metric": "percentage of rhythmically bursting septohippocampal neurons",
        "n_analyzed": null,
        "CI_or_error": null,
        "text_access": "abstract_only",
        "n_definition": "septohippocampal neurons recorded in rats",
        "scope_region": "medial septum-diagonal band of Broca",
        "study_system": "rats, urethane-anesthetized and unanesthetized",
        "taxonomic_level": "species (rat)",
        "scope_population": "septohippocampal neurons",
        "value_source_sentence": "The percentage of RB neurons decreased significantly as compared with controls (17 vs. 41% for SHNs and 5 vs. 19% for unidentified septal neurons).",
        "experimental_conditions": "192 IgG-saporin cholinergic lesion vs control"
      }
    ],
    "comparison_id": "fig_sec4_septohippocampal_rb_neurons",
    "comparison_type": "quantitative comparison of cholinergic lesion effects",
    "homogeneity_check": {
      "caveats": [
        "Single study comparison (control vs lesion within same experiment)",
        "Different states examined (urethane-anesthetized vs unanesthetized)",
        "In unanesthetized lesioned rats, no RB septal neurons found during arousal (0% vs 25% in controls)"
      ],
      "comparable": true
    },
    "suggested_plot_type": "bar_with_errorbars"
  },
  "section_id": "section_04_evidence",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation/blob/95db5c630fe54e183d9c452cf826ce502d4a872d/evidence/section_04_evidence.json",
  "target_ref": "wiki_page:computationalreviewneuromodulation-04",
  "review_repo": "ComputationalReviewNeuromodulation",
  "section_ref": "wiki_page:computationalreviewneuromodulation-04",
  "source_path": "evidence/section_04_evidence.json",
  "source_refs": [
    "paper:paper-fecc55f0a0e1"
  ],
  "section_title": "Acetylcholine: Brain-Wide Modulation of Attention, Memory, and Cortical State",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95db5c630fe54e183d9c452cf826ce502d4a872d",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation"
  },
  "generation_status": "complete",
  "review_bundle_ref": "analysis_bundle:ab-a3dbbaf9b625",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation/blob/95db5c630fe54e183d9c452cf826ce502d4a872d/evidence/section_04_evidence.json",
  "commit_sha": "95db5c630fe54e183d9c452cf826ce502d4a872d",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation"
}