Connectomic resolution: MICrONS and the mouse cortical wiring matrix
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1CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
4CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
6CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
7CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
8CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0 The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 The horizontal wiring rules surveyed in{ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 2CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 2CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 2CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
2CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 2CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4 Three early datasets set the methodological grammar that MICrONS later inherited. The first, 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5, imaged a 450 × 350 × 52 µm volume of mouse V1 containing approximately 1,500 cell bodies and used it to test whether inhibitory interneurons receive convergent excitatory input from pyramidal cells with widely varying orientation preferences. The Bock 2011 volume answered that question affirmatively for excitatio... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
4CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
4CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
4CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 4CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 5CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
5CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 6CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 6CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
6CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2 These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines 6CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM 6CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4 — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi... -
6CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 The MICrONS dataset spans a cubic-millimetre volume of mouse visual cortex (1.3 × 0.87 × 0.82 mm in vivo) co-registering two-photon calcium imaging with serial-section transmission EM, and bridges the function-to-connectivity gap that the earlier landmarks could only sketch within single cortical layers 6CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6. Automated detection identified ~524 million synaptic clefts across the two MICrONS s... -
6CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 The MICrONS dataset spans a cubic-millimetre volume of mouse visual cortex (1.3 × 0.87 × 0.82 mm in vivo) co-registering two-photon calcium imaging with serial-section transmission EM, and bridges the function-to-connectivity gap that the earlier landmarks could only sketch within single cortical layers 6CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8. Automated detection identified ~524 million synaptic clefts across the two MICrONS s... -
6CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 The MICrONS dataset spans a cubic-millimetre volume of mouse visual cortex (1.3 × 0.87 × 0.82 mm in vivo) co-registering two-photon calcium imaging with serial-section transmission EM, and bridges the function-to-connectivity gap that the earlier landmarks could only sketch within single cortical layers 7CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0. Automated detection identified ~524 million synaptic clefts across the two MICrONS s... -
7CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 The MICrONS dataset spans a cubic-millimetre volume of mouse visual cortex (1.3 × 0.87 × 0.82 mm in vivo) co-registering two-photon calcium imaging with serial-section transmission EM, and bridges the function-to-connectivity gap that the earlier landmarks could only sketch within single cortical layers 7CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2. Automated detection identified ~524 million synaptic clefts across the two MICrONS s... -
7CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 The MICrONS dataset spans a cubic-millimetre volume of mouse visual cortex (1.3 × 0.87 × 0.82 mm in vivo) co-registering two-photon calcium imaging with serial-section transmission EM, and bridges the function-to-connectivity gap that the earlier landmarks could only sketch within single cortical layers 7CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4. Automated detection identified ~524 million synaptic clefts across the two MICrONS s... -
7CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 7CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
7CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 7CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
7CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 3CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
3CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 8CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference0. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
8CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference1 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 8CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference2. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
8CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference3 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 8CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference4. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
8CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference5 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 8CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference6. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
8CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference7 The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets 8CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference8. Perisomatic-ultrastructure feature classification reaches 94,010 high... -
8CitationThe horizontal wiring rules surveyed in {ref}
sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference9 The same MICrONS volume supports two non-aligned accounts of excitatory cell-type structure: the unsupervised dendritic-skeleton analysis of 2CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference00 reads excitatory morphology as a continuum across V1, AL, and RL, while the morphology-classifier pipeline used to predict MET-types in inhibitory cells 2CitationThe horizontal wiring rules surveyed in {ref}sec-horizontalwere inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...content/06_connectomic_micons.md:line 5Open reference01 is more naturally applied if excitatory categories are discrete. Whether the wiring rules in this sec... -
... 138 additional anchors in refs_json
References
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- [Kasthuri2015] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Lee2016] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [TheMICrONSConsortium2025] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Ding2025] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Ko2011] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Cossell2015] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Hage2022] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Seeman2018] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Lefort2009] “The horizontal wiring rules surveyed in {ref}`sec-horizontal` were inferred from quad-patch recordings and bulk axonal tracers; both estimate connectivity indirectly, the former through a sampling of pairs reachable by an electrode array and the latter through a fluorescence projection that conflates synaptic and non-synaptic axonal passage. Volumetric electron microscopy (EM) replaces these proxies with a determini...”
- [Collman2015] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Mishchenko2010] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Berning2015] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Schmidt2024] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Meirovitch2023] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Meirovitch2026] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Yin2020] “These three studies — together with conjugate light-electron array tomography that mapped synaptic protein composition onto EM-reconstructed spines [Collman2015] and the earlier hippocampal-neuropil reconstructions that calibrated synapse density estimates against ground-truth EM [Mishchenko2010] — established the working tradeoff that has shaped every subsequent dataset. Sub-millimetre volumes can resolve every spi...”
- [Celii2025] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Elabbady2025] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Dorkenwald2022] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Dorkenwald2023] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Pedigo2026] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Mahalingam2022] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Gamlin2025] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Weis2025] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Tumma2025] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Wang2025b] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
- [Walker2019] “The infrastructure that surrounds the volume is, for present purposes, as important as the volume itself. NEURD provides automated proofreading of merge errors and feature extraction for ~80,000 neurons across the MICrONS volume and ~15,000 neurons in the H01 human-cortex volume, defining a shared neuron-feature schema across datasets [Celii2025]. Perisomatic-ultrastructure feature classification reaches 94,010 high...”
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