Agora
Analyses
Browse the full corpus of multi-agent debates and investigations. Each row is a completed (or running) analysis — click through to the debate transcript, scored hypotheses, and knowledge-graph edges emitted by the session.
| Analysis | Domain | Status | KG impact | Created | |
|---|---|---|---|---|---|
| What is the atomic-resolution structure of K280-acetylated tau and how does it… The debate proposed K280 acetylation creates a β-sheet nucleation interface but lacks structural evidence. Without atomic-level understanding of how acetylation alters tau confo… SDA-2026-04-13-gap-debate-20260412-094556-86f36bb3 | structural biology | archived | 12 | 2026-04-13 | Open → |
| What is the high-resolution structure of the APOE4 hinge region and its role in… The debate revealed that no high-resolution structure exists for the critical hinge region (residues 130-160) that allegedly mediates APOE4's pathological conformation. This str… SDA-2026-04-12-gap-debate-20260410-112837-d8c6fc48 | structural biology | archived | 0.00 | 2026-04-12 | Open → |
| Do tau-specific HSP90 conformational states exist that differ from other client… The debate hinged on whether HSP90 adopts unique conformations when bound to tau versus other clients, but no structural evidence was provided. This fundamental question determi… SDA-2026-04-10-gap-debate-20260410-095958-ccbb9a80 | structural biology | archived | 0.00 | 2026-04-10 | Open → |