The subthalamic nucleus sends a selective projection to parvalbumin-expressing…

{
  "n": null,
  "doi": "10.1523/eneuro.0417-21.2023",
  "claim": "The subthalamic nucleus sends a selective projection to parvalbumin-expressing interneurons of the dorsal striatum, providing a direct STN-to-striatum feedback in mouse.",
  "cite_key": "Kondabolu2023",
  "evidence": "Anterograde AAV tracing and slice ePhys of STN→PV-interneuron synapses in mouse striatum.",
  "effect_size": "see source sentence",
  "text_access": "fulltext",
  "study_system": "mouse (AAV anterograde + slice ePhys)",
  "source_cluster_id": "cluster_02",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Subthalamic nucleus neurons commonly provide reliable inputs to striatal parvalbumin-expressing interneurons Monosynaptic retrograde tracing has revealed some quantitative differences in the glutamatergic cortical and thalamic inputs to dorsal striatal dSPNs and PV interneurons ( Choi et al., 2019 ), raising the possibility that STN inputs to these two striatal cell types might also differ.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Our tracing studies showed that the connectivity from STN neurons to striatal parvalbumin-expressing interneurons is significantly higher (∼4- to 8-fold) than that from STN to any of the four other striatal cell types examined."
}

[
  "paper:paper-a68991ea4c78"
]

Subthalamic nucleus neurons commonly provide reliable inputs to striatal parvalbumin-expressing interneurons Monosynaptic retrograde tracing has revealed some quantitative differences in the glutamatergic cortical and thalamic inputs to dorsal striatal dSPNs and PV interneurons ( Choi et al., 2019 ), raising the possibility that STN inputs to these two striatal cell types might also differ.

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