Details
- scope
- adult male and female mouse, dorsal striatum, PV-Cre
- claim_text
- Subthalamic nucleus glutamatergic neurons project to dorsal striatum with strong (~4–8-fold) bias toward parvalbumin-expressing GABAergic interneurons, enabling robust monosynaptic excitation of striatal PV interneurons.
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- effect_size
- 4–8-fold higher STN connectivity to PV interneurons vs other striatal cell types
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- Our tracing studies showed that the connectivity from STN neurons to striatal parvalbumin-expressing interneurons is significantly higher (∼4- to 8-fold) than that from STN to any of the four other striatal cell types examined.
- study_system
- adult male and female mouse, dorsal striatum, PV-Cre
- section_title
- Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 2, "doi": "10.1523/eneuro.0417-21.2023", "claim": "Subthalamic nucleus glutamatergic neurons project to dorsal striatum with strong (~4–8-fold) bias toward parvalbumin-expressing GABAergic interneurons, enabling robust monosynaptic excitation of striatal PV interneurons.", "cite_key": "Kondabolu2023", "evidence": "", "effect_size": "4–8-fold higher STN connectivity to PV interneurons vs other striatal cell types", "text_access": "fulltext", "study_system": "adult male and female mouse, dorsal striatum, PV-Cre", "source_cluster_id": "cluster_10", "replication_status": "replication_unknown", "claim_source_sentence": "Our tracing studies showed that the connectivity from STN neurons to striatal parvalbumin-expressing interneurons is significantly higher (∼4- to 8-fold) than that from STN to any of the four other striatal cell types examined.", "replication_evidence_dois": [], "effect_size_source_sentence": "Our tracing studies showed that the connectivity from STN neurons to striatal parvalbumin-expressing interneurons is significantly higher (∼4- to 8-fold) than that from STN to any of the four other striatal cell types examined." }- source_refs
[ "paper:paper-a68991ea4c78" ]
- evidence_refs
[ { "ref": "paper:paper-a68991ea4c78" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }