Details

scope
To address this, we conducted monosynaptic retrograde tracing from genetically-defined populations of dorsal striatal neurons in adult male and female mice, quantifying the connectivity from STN neuro
claim_text
In parallel, we used a combination of <i>ex vivo</i> electrophysiology and optogenetics to characterize the responses of a complementary range of dorsal striatal neuron types to activation of STN axons.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
effect_size
95%
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
Our results collectively reveal that the subthalamostriatal projection is highly selective, providing relatively rich and efficacious glutamatergic inputs to GABAergic parvalbumin (PV)-expressing interneurons.
study_system
To address this, we conducted monosynaptic retrograde tracing from genetically-defined populations of dorsal striatal neurons in adult male and female mice, quantifying the connectivity from STN neuro
section_title
Pallidal Organization and the Disinhibition Principle
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1523/eneuro.0417-21.2023",
  "claim": "In parallel, we used a combination of <i>ex vivo</i> electrophysiology and optogenetics to characterize the responses of a complementary range of dorsal striatal neuron types to activation of STN axons.",
  "cite_key": "Kondabolu2023",
  "evidence": "",
  "effect_size": "95%",
  "text_access": "fulltext",
  "study_system": "To address this, we conducted monosynaptic retrograde tracing from genetically-defined populations of dorsal striatal neurons in adult male and female mice, quantifying the connectivity from STN neuro",
  "source_cluster_id": "cluster_04",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Our results collectively reveal that the subthalamostriatal projection is highly selective, providing relatively rich and efficacious glutamatergic inputs to GABAergic parvalbumin (PV)-expressing interneurons.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Approximately 90–95% of striatal neurons can be classified as spiny projection neurons (SPNs), which may then be further divided into, for example, populations giving rise to the direct pathway or indirect pathway ( )."
}
source_refs
[
  "paper:paper-a68991ea4c78"
]
evidence_refs
[
  {
    "ref": "paper:paper-a68991ea4c78"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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